About

Explore Carbonic Anhydrase Pathways

Comprehensive genomic, transcriptomic, and epigenetic data visualization for the human carbonic anhydrase gene family. An integrated platform for exploring 15 CA isozymes with interactive visualizations across multiple biological contexts and experimental systems.

15
CA Genes
7
Data Categories
15+
Data Sources
53
GTEx Tissues
33
TCGA Cancers
931
TFs Profiled
Comprehensive Coverage

Complete coverage of 15 human carbonic anhydrase genes spanning all functional classes: cytosolic (CA1, CA2, CA3, CA7, CA13), mitochondrial (CA5A, CA5B), membrane-associated (CA4, CA9, CA12, CA14), secreted (CA6), and CA-related proteins (CA8, CA10, CA11).

Multi-Source Integration

Integrates data from major genomics databases:

GTEx (V10) Human Protein Atlas FANTOM5 TCGA (33 cancers) UCSC Xena DepMap CELLxGENE Tahoe100m ENCODE ChIP-Atlas ClinVar Human Methylation Atlas MSigDB Ensembl / NCBI
How to Use CABase
1
Select Gene
Use the sidebar to choose any carbonic anhydrase gene
2
Explore Tabs
Genomic context, expression, survival, co-expression networks, correlation, and more
3
Ask the AI
Use the floating assistant to query 23K+ CA publications in real-time
4
Export
Download figures (SVG/PNG) and data tables (CSV/TSV/XLSX)
AI Research Assistant

Query-driven AI assistant powered by a custom RAG pipeline over 23,000+ carbonic anhydrase publications. Ask questions about gene function, expression patterns, clinical relevance, and pathway interactions.

Try: "What cancers show high CA5A expression in single-cell data?"

Parkkila Group · Department of Anatomy · Tampere University

AI-Generated Gene Summary

Select a gene from the sidebar to view AI-generated summaries across genomic, expression, pathway, functional, and clinical dimensions

Single Cell RNA Expression - CELLxGENE

Select a gene and tissue to view expression data

Single Cell RNA Expression - Tahoe100m

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Tahoe100m Detailed Expression Data

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